There is a release of norepinephrine from your descending inhibitory bulbospinal neurons that binds to alpha-2-receptors during the dorsal horn to minimize afferent discomfort transmission and create analgesia. Thus, prescription drugs like clonidine that focus on alpha-two receptors can affect the transmission of soreness. : linked to, served by, https://carlx078vnd8.wikiadvocate.com/user