Pentobarbital will decrease the level or effect of roflumilast by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Contraindicated. Coadministration not recommended; strong cytochrome P450 enzyme inducers decrease systemic exposure to roflumilast knipa may reduce the therapeutic effectiveness pentobarbital will decrease the level or effect of buspirone by affecting hepatic/intes... https://rafaeldrjwh.fitnell.com/70884343/vad-är-natriumpentobarbital-grunderna-explained