At three times submit-MPTP, we uncovered substantial microglial activation and up-regulation of CB2 cannabinoid receptors inside the ventral midbrain. Treatment method with WIN or even the CB2 receptor agonist JWH015 (four mg/kg, intraperitoneal) lowered MPTP-induced microglial activation, While genetic ablation of CB2 receptors exacerbated MPTP systemic toxicity. Moreover, Long-term ... https://win55.clinic/casino