CRC has an immunosuppressive TME which prevents the development of an efficient response to ICB therapies. There exists Therefore an urgent have to determine the methods reprogram this suppressive TME to be able to greatly enhance immunotherapy efficacy. In The present review, we employed CRISPR KO screens to find genes https://chir-09076161.blog5star.com/28898275/the-smart-trick-of-e7449-that-no-one-is-discussing